Vitamin B3-Based Biologically Active Compounds as Inhibitors of Human Cholinesterases

Synthesis of Some Nitrogen Functional Derivatives of 5-substituted-6-azauracil as Biologically Active Compounds

3-Arylhydrazono-2,4-dioxo-4-phenylbutanoates have been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides. Reactions of the 3-arylhydrazono-2,4- dioxo-4-phenylbutanoates with 1-aminoguanidine, semicarbazide, and thiosemicarbazide gave 5-substituted 2-imino-6-azauracil (3a), 6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds ...

Oligonucleotides and polynucleotides as biologically active compounds.

Nucleic acids are involved in the most important processes occurring in living cells and possess an enormous potential for specific interactions with different biopolymers. Specificity of recognition of DNA and RNA species by complementary nucleic acids is unique in the world of biopolymers. A great number of the proteins involved in processes of replication, transcription, and translation are ...

Pomegranate Fruit as a Rich Source of Biologically Active Compounds

Pomegranate is a widely used plant having medicinal properties. In this review, we have mainly focused on the already published data from our laboratory pertaining to the effect of methanol extract of pericarp of pomegranate (PME) and have compared it with other relevant literatures on Punica. Earlier, we had shown its antiproliferative effect using human breast (MCF-7, MDA MB-231), and endomet...

synthesis of some nitrogen functional derivatives of 5-substituted-6-azauracil as biologically active compounds

Effect of Cinnamon and its Biologically Active Compounds on the Components and Symptoms of Metabolic Syndrome

Background and purpose: Metabolic syndrome refers to a set of diseases including insulin resistance, high blood glucose levels, obesity, high blood pressure, and dyslipidemia. The cinnamon plant is a member of the Lauraceae family and is considered a universal medicinal plant. Traditional medicine studies reported the therapeutic effects of this plant in the reduction of blood glucose levels, b...